Working with Biological Materials and Recombinant DNA

Labs Using Biomedical Agents

Researchers conducting research with infectious agents, toxins, human cells/blood/tissue, recombinant DNA or other bio-hazardous agents must have their research approved in advance by the Institutional Biosafety Committee (IBC) by completing a Biohazardous Use Authorization (BUA) form. IBC and BUA information and resources are available at the Biosafety webpage.  BUA approvals are valid for three years.  The PI is responsible for obtaining timely renewals from the IBC.  Without current approval, no research activity involving these materials may be conducted.

PIs working within a laboratory rated BSL-2 or higher, or within which hazardous materials or equipment are used, should develop written laboratory safety plans.  These plans should list required protective equipment (e.g., type of glove, eyewear), and include procedures for containment failure, spills, and emergency response.

Also, if shipment of biological materials (e.g., blood, serum, and other potentially infectious agents) and/or dry ice will occur, shipping training is required.  Registration for this class (and all EH&S courses) can be found on the EH&S training registration page.  For any biosafety related questions, please contact the Biosafety Office at biosafety@usc.edu.